Studies for similar testing should be done with clinical evaluation. Regarding choice and proper dosing of antibiotics to be given. MIC misleads physician for organism’s drug susceptibility
Conclusions : Device associated bacterial biofilms are the major source of infections in patients ofĬritical care setup. MBEC was higher for all the antibiotics as compared to MIC exceptĪmikacin MBEC for Pseudomonas was the same as MIC. Results : Colonization by Klebsiella pneumoniae, Acinetobacter baumanni and Pseudomonas aeruginosa w as prevalent bacterial isolates in medicalĭevices. StatisticalĪnalysis Used : Results will be discussed in the form of percentages. Amikacin, ciprofloxacin, trimethoprim-sulfamethoxazole, vancomycin, Were used as pegs which provide d surface for Assay has been developed for the use with flat bottom, 96-well microtiter plates. Strains were identified by tissue culture plate method & tube method.īiofilm-producing and non-biofilm forming reference strains were used asĬontrols.
Medical devices which were inserted in hospitalized patients. Methods and Material : The study was carried outĭuring January 2014 to March 2014 on 50 positive bacteriological cultures of SettingsĪnd Design : Random sampling with experimental study at tertiary care Aims : Assessment of biofilm productionĪnd comparison of the MIC and MBEC assays evaluate differences in theĪntibiotic sensitivity patterns of different clinical bacterial isolates from Measure s the determination to be made for a biofilm susceptibility to antibiotics. The Minimum Biofilm Eradication Concentration (MBEC) Context : MIC results can be misleading for treatment
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